Wednesday, October 4, 2017

Improve Your Gut Health With Amylase!

As new research places an increasing emphasis on gut health and digestion as a component of optimal health. Digestive enzymes are an important part of this equation as they are essential for getting the nutrients out of the food you eat. Amylase is one of three major enzymes responsible for digesting food and extracting nutrients from the body. Amylase breaks starch down into isomaltose and maltose, two sugar units, as well as other key enzymes. Foods high in starch like bread, corn, and grains, require optimal amylase levels for digestion and metabolism. Without it, the potential fuel from these foods goes to waste.

Amylase deficiency can result in impaired metabolic function, specifically of carbohydrates. Larger molecules cannot be effectively broken down leading to unbalanced blood sugar.

Reasons to supplement with Amylase:

- Improved Digestion

- Increased Energy Levels

- Reduced Inflammation

- Improved Blood Sugar

- Anti-Aging Effects



 


Tuesday, October 3, 2017

Weight Loss & the Immune System


Extreme Exercise

Vigorous exercise may potentially lower your immune functioning. Olympians -- who often engage in extreme exercise during peak training months -- report having a lower resistance to upper respiratory tract infections, colds and sore throats. According to a 2001 literature review by the President’s Council on Physical Fitness and Sports, over-training is associated with physical illnesses. Thus, the intensity of your workout or calorie expenditure is indicative of your infection risk.

Moderate Caloric Restriction

Moderate caloric restriction increases longevity and boosts the immune system to chronic conditions, according to Michigan State University. However, researchers found greater calorie consumption and fat reserves yield a better prognosis in flu outcomes. The flu naturally curbs the body’s appetite, but subsequent eating behavior can dictate the rate an individual overcomes the flu. According to the MSU study, mice engaging in a calorie-restricted diet lost more weight, possessed longer recovery times and revealed increased mortality rates than their non-restricting counterparts.

Overweight Status

Overweight status is a risk factor for poor immune functioning. Fat tissue generates immune hormones. Specialized immune hormones called cytokines react to areas of infection and bodily injuries. According to University of New Mexico researcher Len Kravitz, excess body fat can cause these hormones to overreact, contributing to chronic inflammation. Chronic inflammation is associated with diabetes and heart disease. Weight loss decreases the circulating immune hormones contributing to this inflammation.

http://www.livestrong.com/article/479646-does-losing-weight-lower-your-immune-system/

Wednesday, August 30, 2017

Forskolin - An Ancient Herb That Melts Fat Away!

The use of plants as medicine has existed since prehistoric times. Literally sources give evidence of the use of medicinal plants as far back as 3000BC in ancient Egypt, India, and China. Despite the thousands of years of success of certain plants as medicine, the FDA strictly prohibits making claims on such products, making it difficult for medical providers to properly inform their patients and instead leading them to use "FDA approved" products which often include harmful and even deadly side effects.

Coleus forskohlii is a plant native to subtropical and warm temperate habitats and a member of the mint family. The plant has been used since ancient times as a medicinal herb in India, which is also believed to be the place of its origin. Coleus forskohlii has been grown in India, Nepal, Burma, Sri Lanka, and Thailand.

The genus Coleus includes nearly 200 species distributed in tropical and subtropical regions. Of the 200 species of Coleus, only Coleus forskohlii contains forskolin, a bio-active compound with multiple pharmacological benefits.

Although forskolin has been known for its wide range of health benefits, its unique activity as a non-adrenergic stimulator of enzyme adenylate cyclase attracted the attention of researchers to explore its supportive role in managing body weight and promoting lean body mass.

The primary mode of action of forskolin is by increasing concentrations of cyclic AMP (cAMP) through activation of adenylate cyclase, an enzyme involved in the production of cAMP. cAMP functions as a messenger which controls glycogenolysis and glycogenesis. Increased levels of cAMP leads to an activation of the enzymes protein kinase and hormone sensitive lipase. Hormone sensitive lipase is essential for providing energy by mobilizing stored fats through lipolysis.
"Typically, an increase in cAMP levels leads to subsequent activation of protein kinase. Protein
kinase has been shown to activate the hormone-sensitive lipase that is involved in the breakdown of
triglycerides, known as building blocks of fatty tissue"1

Many ingredients available for weight management that are designed to reduce body fat do so with little regard for, or at the expense of, lean muscle mass. This is undesirable because it is believed that an increase in muscle mass upregulate's the body's metabolism, as muscle requires energy to sustain its mass and in turn helps burn additional body fat throughout the day.

"Lean body mass consists of muscles, vital organs, bone, bone marrow, connective tissue and body water. Lean body mass can simply be described as total body weight minus fat. The proportion of lean body mass to fat not only determines the body's aesthetic look, but more importantly determines a person's physical fitness, health status and risk for morbidity (disease) and premature mortality."2

Clinical studies have shown that forskolin use can result in enhanced lean body mass white promoting fat loss and improving overall body composition.

Studies

An eight week trial involving six overweight women taking forskolin via capsule twice per day saw an average weight loss of 9.17lbs3. Body fat percentage decreased from 33.63% to 25.88% and lead body mass saw an increase from 67% to 74%.

A double-blind, placebo controlled study illustrated the effect of forskolin on body composition. Thirty men were assigned forskolin or placebo for a 12-week trial4. Although the participants did not experience significant weight loss, the forskolin group saw a significant increase in lean body mass, from 61% to 64.7% and a decrease in fat mass, 35.17% to 31.03% compared to the placebo group which did not experience any significant change in body composition



1. Bagchi, D., & Preuss, H. (2012). Obesity: Epidemiology, Pathophysiology, and Prevention. New York, NY: CRC Press

2. Badmaev, V., Majeed, M. Coleus forskohlii: Fat-fighting and more. Nurition Industry Executive.

3. Badmaev, V., Majeed, M., Conte, A., & Parker, J. (2002). Diterpene Forskolin. NutraCos.

4. Godard, M., Johnson, B., & Richmond, S. (2005). Body Composition and Hormonal Adaptions... Obesity Research.
 

Wednesday, August 16, 2017

Cortisol & DHEA

Cortisol is a stress hormone produced by the adrenals. This hormone is released when you experience stress and is an important hormone in your body working to maintain homeostasis by determining your energy needs.

DHEA is a base hormone used to manufacture all of the steroid hormones. Levels deplete after the age of 25. DHEA effectively antagonizes the effects of cortisol. Low levels of DHEA are often found in those with adrenal fatigue.

The ratio between cortisol and DHEA has numerous effects on the body. An elevated ratio (high cortisol) can lead to suppressed immune function, impaired metabolism, loss of memory, breakdown of collagen and bone, and other undesirable effects.




Increased cortisol levels causes the body to access protein stores to create energy, which blocks the effect of insulin leading to increased insulin resistance. Cortisol also can cause stored triglycerides to be relocated to the visceral fat cells, primarily the ones in the abdomen and under muscle.

If you struggle with insulin resistance or obesity, elevated cortisol may be the cause. If that is the case, DHEA could be the cure.








McEvoy, M. (2011). Cortisol & DHEA: The Major Hormone Balance. Retrieved from: https://metabolichealing.com/cortisol-dhea-the-major-hormone-balance/

DeLacey, E. Cortisol, Stress and Body Fat. Retrieved from: http://www.fitday.com/fitness-articles/nutrition/healthy-eating/cortisol-stress-and-body-fat-myth-versus-fact.html

Wednesday, August 9, 2017

Hydroxycitric Acid

Bio-Citrin - Garcinia Cambogia with Bioperine and Chromium Polynicotinate  

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Helps with long-term weight management by minimizing the impact of carbohydrates. The hydroxycitric acid (HCA) from Garcinia Cambogia blocks the enzyme ATP-citrate lyase, which is responsible for converting carbohydrates to fat. This allows more glucose to be used by the cells as energy, while decreasing the amount of new fat produced and increasing satiety.

Hydroxycitric acid has been proven in multiple studies to be a safe and effective weight loss ingredient which suppresses appetite and inhibits fat synthesis.

Read more about the benefits of HCA in our newest white paper: Carbohydrate Metabolism - Slowing Lipid Synthesis. 

 

Monday, July 17, 2017

Dieting & Your Immune System

Your immune system helps guard your body from germs, viruses, and other threats. Ongoing stress can take its toll on your immune system making you more vulnerable to colds and flu. The impact stress has on your immune system was observed in medical students during a 10 year study1:

"Researchers found that the students' immunity went down every year under the simple stress of the three-day exam period. Test takers had fewer natural killer cells, which fight tumors and viral infections. They almost stopped producing immunity-boosting gamma interferon and infection-fighting T-cells responded only weakly to test-tube stimulation."

Stress can be caused by many factors, including dieting. Studies have found that dieters produced higher levels of the harmful stress hormone cortisol2. In addition to dieting being a large cause of stress, a restricted diet may further reduce the effectiveness of your immune system due to nutrient deficiencies.

For the above reasons it is important for dieters to supplement their immune system with nutrients they may not be getting in their diet.

Immuneplex™ is a unique formulation with the purpose of aiding the immune system with
essential vitamins and minerals required for proper function.







References:
1. Kiecolt-Glaser, J. K., Glaser, R. (1993). Mind and immunity. Mind/Body Medicine (pp. 39-59). New York: Consumer Reports.

2. Hagan, P. (2010). Dieting really CAN harm your health. Daily Mail UK. Retrieved from: http://www.dailymail.co.uk/health/article-1266591/Dieting-really-CAN-harm-health-Slimmers-higher-risk-heart-disease-cancer.html

Friday, June 23, 2017

Oral vs. Sublingual

When you swallow a pill, it travels through your gastrointestinal tract. It passes through the stomach, the intestines, and the liver before the medication is delivered to where it is needed. Sublingual (under the tongue) applications bypass the GI tract, as they are absorbed by the blood vessels in your mouth, getting the medication directly to the bloodstream.


That is not to say that oral applications do not work. In a 4-week test of sublingual B12 vs. oral B12, the oral group saw B12 levels rise by 164%. The sublingual group saw an even more impressive rise of 206% from baseline levels. 



Legere Pharmaceuticals has specially formulated sublingual sprays for optimal absorption:


Be-Thin contains Methylcobalamin B12, amino acids including Acetyl-L-Carnitine, and lipotropic nutrients Methionine, Inositol, and Choline.  


Myoden Spray contains Adenosine Monophosphate, a naturally occurring nucleotide which may have a positive impact on ATP production and fat utilization via AMPk activation.

Reference:
Sharabi, A., Cohen, E., Sulkes, J., Garty, M. (2003). Replacement therapy for vitamin B12 deficiency: comparison between the sublingual and oral route. NCBI. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884303/